Superspher® RP-select B is a highly reproducible traditionally produced spherical silica gel carriers with reversed phase properties and the hydrophobicity of a C-8 phase. This carrier is very well suited for the separation of basic compounds, but with still good properties for the determination of neutral and acidic compounds. The high performance silica carrier with a particle size of 4µ yields an excellent pressure/separation performance ratio.Thissorbent is packed into LiChroCART®10-2HPLC guard columns, to be used in connection withLiChroCART® HPLC cartridges, packed with Superspher®RP-select B, 4µ. The connection is being accomplished by use of the manu-CART® NT cartrige holder (1.51486).