NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure
- Wide acceptance as routine packings for very different fields of chromatography
- One of the first spherical silicas used in HPLC
- Developed in the early seventies, it became a world-renowned HPLC packing
- Still found in many analytical and preparative application
- An absolutely reliable choice in HPLC
- The largest variety of modified HPLC silicas available on the market
NUCLEOSIL® C8 HD
Octyl modified high density silica phase for HPLC Monomeric modification, endcapped
USP L7
Features
- Hydrophobic, nonpolar phase for RP chromatography
- Particle sizes 5 µm
- Pore size 100 Å
- pH stability 2–8
- Carbon content 13 %
Recommended for separation of moderately to highly polar (water-soluble) compounds
Applications: steroids, nucleosides, cyclodextrins, pharmacological plant constituents
Separation mechanism based on hydrophobic (van der Waals) interactions
Corresponding NUCLEODUR® phase: see NUCLEODUR® C8 Gravity