NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure
- Wide acceptance as routine packings for very different fields of chromatography
- One of the first spherical silicas used in HPLC
- Developed in the early seventies, it became a world-renowned HPLC packing
- Still found in many analytical and preparative application
- An absolutely reliable choice in HPLC
- The largest variety of modified HPLC silicas available on the market
NUCLEOSIL® standard C18 phases
Octadecyl modified silica phases for HPLC, endcapped
USP L1
Features
- Nonpolar, endcapped phases for RP chromatography
- Available pore sizes 50, 100, 120, 300, 500 and 1000 Å
- Available particle sizes 3 µm, 5 µm, 7 µm and 10 µm
- pH stability at 20 °C: 2–8
- Carbon content depending on pore size, e.g.,50 Å (14.5 %), 100 Å (15 % C) - 1000 Å ~ 1 % C
Separation mechanism based on hydrophobic (van der Waals) interactions, slight residual silanol interactions
Corresponding NUCLEODUR® phases: see NUCLEODUR® C18 ec