NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure
- Wide acceptance as routine packings for very different fields of chromatography
- One of the first spherical silicas used in HPLC
- Developed in the early seventies, it became a world-renowned HPLC packing
- Still found in many analytical and preparative application
- An absolutely reliable choice in HPLC
- The largest variety of modified HPLC silicas available on the market
NUCLEOSIL® C18 HD
Octadecyl modified High Density silica phase for HPLC Monomeric modification, endcapped
USP L1
Features
- Hydrophobic, nonpolar phase for RP chromatography
- Pore size 100 Å
- Available particle sizes 3 µm and 5 µm
- pH stability 2–9
- Carbon content 20 %
Suited for separation of basic compounds such as pharmaceuticals
Separation mechanism based on hydrophobic (van der Waals) interactions
Corresponding NUCLEODUR® phase: see NUCLEODUR® C18 Gravity