NUCLEOSHELL® core-shell silica phases for HPLC
NUCLEOSHELL® Core-shell technology provides
- Better resolution at lower back pressure and shorter retention time
- Solid core of silicon dioxide
- Homogeneous shell of porous silica
- Highest efficiency compared to traditional totally porous materials
- Particle size 2.7 µm (core 1.7 µm); specific surface 130 m2/g
- RP 18 and RP 18plus phases are also available with particle size 5 µm (core 3.8 µm); specific surface 90 m2/g
- Lower back pressure also allows use on conventional LC systems
- Pressure stability up to 600 bar
NUCLEOSHELL® RP 18
Core-shell technology silica phase for HPLC , octadecyl modification ODS / BDS) with multi-endcapping, USP L1
Key features:
- Based on core-shell particle technology for fast and efficient HPLC
- Suitable for LC/MS and HPLC at pH extremes (pH 1–11)
- Superior base deactivation, ideal for method development
Technical characteristics:
- Octadecyl modification, multi-endcapped
- Pore size 90 Å
- Particle size 2.7 μm with carbon content 7.8 %
- Particle size 5 µm with carbon content 6.1 %
Recommended application: Overall sophisticated analytical separations, e.g., analgesics, antiinflammatory drugs, antidepressants; herbicides; phytopharmaceuticals; immunosuppressants