NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
- Totally spherical particle shape
- Outstanding surface microstructure
- High pressure stability
- Low metal content
NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® HILIC
Hydrophilic Interaction Chromatography
Key features:
- Ideal for reproducible and stable chromatography of highly polar analytes
- Suitable for analytical and preparative applications
- Very short column conditioning period
Technical characteristics:
- Ammonium – sulfonic acid modified silica
- Pore size 110 Å
- Available particle sizes 1.8 µm (UHPLC), 3 µm and 5 µm
- pH stability 2–8.5
- Carbon content 7 %
Recommended application: Hydrophilic compounds such as organic polar acids and bases, polar natural compounds, nucleosides, oligonucleotides, amino acids, peptides, water soluble vitamins