NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:
- Totally spherical particle shape
- Outstanding surface microstructure
- High pressure stability
- Low metal content
NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® C18 Gravity-SB
Monomeric octadecyl modification with polar selectivity, USP L1
Key features:
- Hydrophobic C18 phase with distinct polar selectivity, ideal for method development, better retention of early eluting substances
- Excellent performance under highly aqueous conditions
- Suitable for LC/MS due to low bleeding characteristics
Technical characteristics:
- Monomeric octadecyl modification, extensive endcapping;
- Pore size 110 Å
- Available particle sizes 1.8 μm (UHPLC), 3 μm and 5 μm
- Carbon content 13 %;
- pH stability 1–9
Recommended application:
- Overall sophisticated analytical separations, especially for polar compounds, e.g., antibiotics, water-soluble vitamins, organic acids