Synonyms: Fibronectin
MDL No.: MFCD00131062
Storage: -20C
EC Number: 289-149-2
UNSPSC Code: 12352200
General description: Fibronectin (FN) is a multifunctional glycoprotein, the gene of which is localized to human chromosome 2q34-36. This gene spans 75kb and contains 50 exons. It exists as two major isoforms, one soluble and one insoluble form. The former is present in plasma, whereas the insoluble form resides in tissues and extracellular matrix (ECM) of cartilage. There are around 20 different forms of FN due to alternative splicing of a variable region and two type III exons called Extra Domains A and B.
Application: Fibronectin from bovine plasma is used for the following applications:. Used for coating the glass coverslips for the culture of decidual stromal cells (DEC). Cell movement assays (culture plates were coated with fibronectin). Cell spreading and immunofluorescence . Protein specificity. Integration of sensor films into microfluidic chips. Histological and Immunohistochemical (IHC) analyses. Used in primary cell cultures from patients with lung carcinoma
RIDADR: NONH for all modes of transport
WGK Germany: 3