Source: Active human recombinant N-terminal His-tagged protein purified from Sf21 cells
Mr: 50.8 kDa
PTEN functions as a key regulatory enzyme in many signal transduction pathways by dephosphorylating proteins and lipids such as Akt and PIP3. Mutation of PTEN results in many human cancers including melanoma and prostate carcinoma, making PTEN an important tumor suppressor.