The IBI Isolate Total Extraction Reagent System is a phenol, chloroform, and guanidine isothiocyanate based scalable solution for extracting high-quality total RNA, as well as simultaneous extractoin of RNA, DNA, and protein from a variety of samples such as blood, buffy coat, plasma, serum, cultured cells, and tissue. IBI isolates are a cost effective alternative for efficient total RNA extractions.