SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells.
SARS-CoV-2 Spike S1 Antibody (HC2001), Human Chimeric is produced from cell culture in vitro under conditions free from animal-derived components.
Isotype: Recombinant human IgG1
Clone:HC2001 (monoclonal antibody)
Purification: Protein A
Conjugation: Unconjugated
Specificity
The product is specific for SARS-CoV-2 Spike Protein S1 subunit and its RBD domain
Concentration
1 mg/ml, supplied in PBS, pH 7.4, containing 0.02% sodium azide.
Storage
Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. Avoid repeated freezing and thawing cycles.
Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA detection: 0.1-10 µg/ml
Other applications: user-optimized