Polyclonal antibody for IL 1 BETA/IL1B detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human. IL 1 BETA/IL1B information: Molecular Weight: 30748 MW; Subcellular Localization: Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins; Tissue Specificity: Expressed in activated monocytes/macrophages (at protein level).
Attributes:
sku: A00101
name: Anti-IL-1 beta/IL1B Picoband™ Antibody
gene_name: IL1B
clonality: Polyclonal
concentration: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
size: 100ug/vial
uniprot_id: P01584
host: Rabbit
immunogen: E. coli-derived human IL-1 beta recombinant protein (Position: A117-S269). Human IL-1 beta shares 78.3% and 77.6% amino acid (aa) sequence identity with mouse and rat IL-1 beta, respectively.
form: Lyophilized
purification: Immunogen affinity purified.
storage: At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
cross_reactivity: No cross reactivity with other proteins.
reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
application_details: Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
applications: WB
reactivity: Human, Mouse, Rat
research_category: Atherosclerosis, Cardiovascular, Cytokines, Immunology, Innate Immunity, Interleukins, Metabolism, Obesity, Vascular Inflammation
synonyms: Interleukin-1 beta;IL-1 beta;Catabolin;IL1B;IL1F2;
gene_full_name: Interleukin-1 beta
molecular_weight: 30748 MW
protein_function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. .
subcellular_localization: Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.
tissue_specificity: Expressed in activated monocytes/macrophages (at protein level).
recommended_detection_systems: Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.