Quinine sulfate, meets USP testing specifications, monograph mol wt. 782.94 ((C20H24N2O2)2 . H2SO4 . 2H2O)

Synonyms: Quinine hemisulfate salt monohydrate; Quinine sulfate (2:1) (salt) dihydrate

Formula: C₂₀H₂₄N₂O₂ · 0.5H₂O₄S · H₂O

Formula Weight: 391.47

CAS No.: 207671-44-1

Application: Use to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites, the toxicity of heme (FP)-complexes and to inhibit mitochondrial ATP-regulated potassium channel.

Biochem/physiol Actions: Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.