Antigen: human 15-LO-2 amino acids 161-179
Host: rabbit
Cross Reactivity: (+) human 15-LO-2; (−) rabbit reticulocyte 15-LO-1 and porcine leukocyte 12-LO-1
Application(s): WB
15-LO-2 oxygenates C15 of arachidonic acid to produce 15(S)-HETE. Expression of 15-LO-2 appears to be restriced to prostate, lung, skin, and cornea and may play a role in the normal development of these tissues.