Antigen: human and rat amino acids 130-149; The sequence is 95% homologous to 5-LO from mouse and hamster
Host: rabbit
Cross Reactivity: (+) human, rat, mouse, hamster, and porcine 5-LO; (−) 12-LO and 15-LO
Application(s): WB
5-LO catalyzes the formation of 5(S)-HpETE from arachidonic acid as well as its subsequent conversion to LTA4.